Basal Tumour

Tumour radiobiology beyond fractionation

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...

intramedulary pearly tumour

the presentation treatment and postoperative progress of two patients with pearly intraspinal eptdermcids is described. in one of the patients the tumour recurred after the first removal. necessitating a second operation. despite serious distur bances of gait both patients improved following surgery. the literature in respect of these tumours. is reviewed

Deregulation of the tumour suppressor genes p14, p15, p16 and p53 in basal cell carcinoma

Background Basal cell carcinoma (BCC) is a locally aggressive slowly growing tumour that rarely metastasizes and is mostly seen in older members of the population. Objectives To determine the involvement of the tumour suppressor genes p14, p15, p16 and p53 in BCC. Methods We investigated the integrity of the CDKN2A locus in 15 BCC samples by analysing the presence of allelic imbalance ⁄ loss of...

Basal Cell Carcinoma Surgery: Simple Undermining Approach in Two Patients with Different Tumour Locations

Basal cell carcinoma (BCC) is the most common human malignancy, accounting for the majority of all non-melanoma skin cancers (NMSC). In the past several decades the worldwide incidence of BCC has constantly been increasing. Even though it is a slow growing tumour that, left untreated, rarely metastasizes, it has a distinctive invasive growth pattern, posing a considerable risk for local invasio...

Painful eye caused by basal cell carcinoma of the eyelid: tumour enlargement resulting in trichiasis.